Clinically Proven Skincare: Peer-Reviewed & Medical Journal Published

Clinically Proven Skincare Backed by Peer-Reviewed, Published Studies

At Dr. Few Skincare, we believe “clinically proven” should mean exactly that. While many skincare brands make claims about clinical results, very few can back them with the gold standard of evidence: institutional review board (IRB)-approved, peer-reviewed clinical studies published in respected medical journals.

What Does Peer-Reviewed Mean — and Why Is It Important?

When a skincare study is peer-reviewed and published in a reputable medical journal, it means the research has been rigorously evaluated by independent experts in dermatology, plastic surgery, and aesthetic medicine. These experts review the data, methods, and results to ensure the research meets the highest standards for accuracy, transparency, and scientific merit.

This is not marketing spin or internal testing designed for favorable results–which is how many brands validate their claims. It’s objective science, and it’s extremely rare in the skincare industry.

When you choose products from Dr. Few Skincare, you’re choosing formulas that have passed this highest bar of clinical proof.

Our commitment to scientific integrity isn’t just a talking point — it’s documented in three IRB-approved, peer-reviewed clinical studies published in the Aesthetic Surgery Journal Open Forum, a leading medical publication in aesthetic medicine.

Why This Matters for You

Very few brands conduct peer-reviewed, medical journal-published studies. Most rely on small, internal brand-run trials that aren’t reviewed by outside experts — meaning the results are biased by design.

When you invest in medical-grade skincare, you deserve to know that the products you’re applying every day have been proven to work — and proven to be safe — in the real world, on real people, under real medical scrutiny.

That’s the Dr. Few Skincare difference:

  • Peer-reviewed, medical journal-published proof
  • Tested for efficacy and tolerability across diverse skin types
  • Clinically shown to work alongside professional cosmetic treatments
  • Formulated for real results — not just marketing fluff
STUDY 1

The Stackable Treatment Study (2024)

This long-term clinical trial evaluated the daily use of our Stackable Treatment Routine, a 4-product skincare system designed to support skin health while complementing in-office aesthetic procedures. Over a 1-year period, patients used: Gentle Exfoliating Cleanser, Moisture Complete, Tinted Mineral Sunscreen SPF 30 and Clean Retinol

Stackable Treatment Core Four

100%
saw improvement in skin roughness, dehydration, visible pores, and scars.

93%
saw improvement in pigmentation.

89%
saw improvement in vascular concerns.


0%
adverse reactions were reported — even when used alongside treatments like lasers, microneedling, and chemical peels.

All results

C Serum

100%
saw improvements in severe wrinkles and scars

100%
experienced minimal side effects or irritation

100%
felt more confident in the appearance of their skin

All results
View product View product

Stackable Treatment Core Four

100%
saw improvement in skin roughness, dehydration, visible pores, and scars.

93%
saw improvement in pigmentation.

89%
saw improvement in vascular concerns.


0%
adverse reactions were reported — even when used alongside treatments like lasers, microneedling, and chemical peels.

All results

C Serum

100%
saw improvements in severe wrinkles and scars

100%
experienced minimal side effects or irritation

100%
felt more confident in the appearance of their skin

All results
View product View product

“In my practice and in my skincare line, science comes first. Every Dr. Few Skincare product is held to the same standard I use in clinical medicine—our products are backed by rigorous testing and published in peer-reviewed medical journals.”

DR. JULIUS FEW

STUDY 2

The Clean Retinol Study (2022)

This prospective clinical trial tested the efficacy and tolerability of our Clean Retinol a novel formula designed to deliver visible anti-aging results while minimizing the irritation often caused by retinol.

Clean Retinol

100%
saw improvements in severe wrinkles and scars

100%
experienced minimal side effects or irritation

100%
felt more confident in the appearance of their skin

All results

C Serum

100%
saw improvements in severe wrinkles and scars

100%
experienced minimal side effects or irritation

100%
felt more confident in the appearance of their skin

All results
View product View product

Clean Retinol

100%
saw improvements in severe wrinkles and scars

100%
experienced minimal side effects or irritation

100%
felt more confident in the appearance of their skin

All results

C Serum

100%
saw improvements in severe wrinkles and scars

100%
experienced minimal side effects or irritation

100%
felt more confident in the appearance of their skin

All results
View product View product

Proven Safe and Effective for All Skin Tones and Types

All our published clinical studies included patients with diverse skin tones and types, including Fitzpatrick skin types II through VI. This means Dr. Few Skincare products have been tested and shown to be safe and effective across a wide range of skin tones, from lighter to deeper complexions.

Additionally, because our formulas were developed by board-certified plastic surgeon Dr. Julius Few, they are designed to be exceptionally gentle, even for patients with sensitive skin, those recovering from in-office cosmetic treatments, or anyone prone to redness and irritation.

STUDY 3

The DermaReverse™ Study (2025)

The efficacy and tolerability of DermaReverse™ was tested in a 6-week, double-blind, placebo-controlled clinical trial published in the Aesthetic Surgery Journal Open Forum, with results verified by independent board-certified plastic surgeons, and third party independent medical journal reviewers.

DermaReverse™: Clinically-Proven Skincare for GLP-1 Users

100%
experienced an improvement in wrinkle appearance.

100%
experienced an improvement in surface roughness.

100%
experienced a reduction in redness.


100%
experienced an improvement in hydration.


100%
agreed DermaReverse™ was gentle enough for daily use. 

All results

C Serum

100%
saw improvements in severe wrinkles and scars

100%
experienced minimal side effects or irritation

100%
felt more confident in the appearance of their skin

All results
View product View product

DermaReverse™: Clinically-Proven Skincare for GLP-1 Users

100%
experienced an improvement in wrinkle appearance.

100%
experienced an improvement in surface roughness.

100%
experienced a reduction in redness.


100%
experienced an improvement in hydration.


100%
agreed DermaReverse™ was gentle enough for daily use. 

All results

C Serum

100%
saw improvements in severe wrinkles and scars

100%
experienced minimal side effects or irritation

100%
felt more confident in the appearance of their skin

All results
View product View product

If you’re serious about evidence-based skincare, look for brands that have done the work — peer-reviewed clinical trials, published in reputable medical journals. At Dr. Few Skincare, we’re proud to set this new gold standard, because your skin deserves nothing less.