DermaReverse™
Morning & Night Treatment
DermaReverse™ is a state-of-the-art skincare solution designed by Dr. Julius Few specifically for GLP-1 users experiencing GLP Face™ and beyond that, anyone with prematurely aging skin. In a clinical trial, people using DermaReverse™ saw dramatic results;*
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100% experienced an improvement in wrinkle appearance
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100% experienced an improvement in surface roughness
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100% experienced a reduction in redness
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100% experienced an improvement in hydration
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100% agreed DermaReverse™ was gentle enough for daily use
Backed by years of surgical expertise and cutting-edge technology, DermaReverse™ is a unique treatment formulated to improve visible sagging, hyperpigmentation and texture, while helping to combat fine lines and dryness.
DermaReverse™ is powered by two proprietary complexes–H2OA™ and HP4™–alongside Sodium Hyaluronate, a derivative of hyaluronic acid, and skin soothing botanicals like Aloe Vera and Chamomile. These ingredients work synergistically to effectively support elastin and collagen production and cellular turnover, without causing irritation. The result? Firmer, smoother, brighter, bouncy skin.
*In a 6-week, double-blind, placebo-controlled clinical trial accepted for publication in the Aesthetic Surgery Journal Open Forum. Results verified by independent board-certified plastic surgeons, and third party independent medical journal reviewers.
Please note: if you are pregnant or breastfeeding, refrain from using this product. Consult a physician prior to using any topical product containing retinoic acid / Vitamin A derivatives.

How to use
It’s so easy to apply
- Step 1 After cleansing, apply 2-3 drops to clean fingertips.
- Step 2 Gently massage a thin layer of the product into the face, neck, and décolletage nightly before bed, careful to avoid the delicate area directly around the eyes.
- Step 3 DermaReverse™ can be used morning and night.
- Step 4 Warning: Always apply an SPF 30+ sunscreen when using during the day.
- Step 5 At night and during the day, follow application of DermaReverse™ with the appropriate moisturizer for your skin type.
Key Ingredients

H2OA™
A bioavailable retinoic acid derivative complex designed for fast absorption into the skin, and quick effectiveness without irritation

HP4™ Peptide Complex
A blend of complementary peptides work together to help stimulate collagen and elastin production, reduce the appearance of fine lines & wrinkles, and reduce irritation.

Sodium Hyaluronate
Derivative of hyaluronic acid that helps improve skin firmness, smooth fine lines, and hydrate the skin

Aloe Leaf Juice
Soothing botanical that reduces skin inflammation and redness

Chamomile
Skin soothing botanical ingredient with skin-protective antioxidant benefits

Calendula
a flower rich in natural antioxidants that protects the skin from free-radical damage, whilst also helping to hydrate, firm and soothe stressed skin
Complete your stackable routine
Whether you call it life-changing, a must-have, or a fan-fave, these products are an instant add to bag.

DermaReverse™
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FAQs
Find answers to commonly asked questions about our product, its use, and expected results.
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In Dr. Few's clinical practice, the volume of patients on GLP-1 therapy presenting with visible changes to skin quality became impossible to ignore. That’s when he began referring to the changes in their skin as 'GLP Face' and 'GLP Skin'—a new pattern that demanded attention.
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Yes, DermaReverse™ has been clinically tested for 2x per day use, both morning and night. If using during the day, always apply a broad spectrum mineral sunscreen of SPF 30 or higher.
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While DermaReverse™ was clinically tested on GLP-1 users, its state-of-the-art ingredients are designed to be used by anyone experiencing visibly aging skin.
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No, this product is specifically designed for people who are on or have been on GLP-1s and not just people with weight-loss associated skin change. DermaReverse™ is designed to address the changes observed in GLP-1 users. However, it is also suitable for those experiencing premature aging of the skin.
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DermaReverse™ contains a proprietary, patent-pending ingredient complex called the H2OA™ Complex. This complex was designed by Dr. Few to deliver a bioavailable form of retinoic acid that can be used twice daily (morning and night) even on skin that is sensitive, experiencing a thinning appearance, or generally sensitive to other forms of Vitamin A, like retinol.
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If used both morning and night on the face, neck, and décolletage areas, one 30mL bottle of DermaReverse™ should last about 30 days.
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We suggest using DermaReverse™ without any other retinol for 6 weeks (per our study protocol) before adding another retinol to your routine. After 6 weeks, if well-tolerated, you can layer it underneath the Clean Retinol from Dr. Few Skincare.
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DermaReverse™ can be started at any time, whether you are on a GLP-1 or not. In our clinical trial, every patient was already using GLP-1 for as little as 6 months, to as long as over 1 year. It is recommended to start using DermaReverse™ before or when you start GLP-1 treatment; but, based on our clinical trial, it's never too late to start.


